Fandom

VroniPlag Wiki

Aeh/017

< Aeh

31.371Seiten in
diesem Wiki
Seite hinzufügen
Diskussion0 Teilen

Störung durch Adblocker erkannt!


Wikia ist eine gebührenfreie Seite, die sich durch Werbung finanziert. Benutzer, die Adblocker einsetzen, haben eine modifizierte Ansicht der Seite.

Wikia ist nicht verfügbar, wenn du weitere Modifikationen in dem Adblocker-Programm gemacht hast. Wenn du sie entfernst, dann wird die Seite ohne Probleme geladen.

Pharmacological investigation of spreading depression propagation in rat neocortical tissues

von Dr. Aziza El Harrak

vorherige Seite | zur Übersichtsseite | folgende Seite
Statistik und Sichtungsnachweis dieser Seite findet sich am Artikelende
[1.] Aeh/Fragment 017 06 - Diskussion
Zuletzt bearbeitet: 2014-04-29 22:36:15 Schumann
Aeh, Fragment, Gesichtet, KomplettPlagiat, SMWFragment, Schutzlevel sysop, Sheikh 2009

Typus
KomplettPlagiat
Bearbeiter
Hindemith
Gesichtet
Yes.png
Untersuchte Arbeit:
Seite: 17, Zeilen: 6-16
Quelle: Sheikh 2009
Seite(n): 22, Zeilen: 7-19
SD cellular correlate is a depolarization shift associated with complete breakdown of the membrane potential that is dependent on the asymmetric intra- and extracellular ion distribution and is maintained by the energy consuming work of membrane pumps. The ability of neurons to generate action potentials is lost during SD, which explains the spreading electrical silence accompanied SD under physiological conditions (Somjen 2001). In [sic] the other hand, epileptic activity is characterized by the paroxysmal depolarization shift, a hypersynchronous network event resulting from a giant excitatory postsynaptic potential. A paroxysmal depolarization shift is the correlate of. [sic] The EPSP is presumably the consequence of synchronous activation of recurrent excitatory pathways (Jonston and Brown, 1984). SD is accompanied by a very large increase in [K+]o. The increase in [K+]o is accompanied by a precipitous drop in [Cl-]o, [Na+]o, and [Ca2+]o. SD cellular correlate is a depolarization shift associated with complete breakdown of the membrane potential that is dependent on the asymmetric intra-/extracellular ion distribution and is maintained by the energy consuming work of membrane pumps. The ability of neurons to generate action potentials is lost during SD, which explains the spreading electrical silence (depression of electrocorticographic activity) accompanied SD under physiological conditions (Somjen 2001). In [sic] the other hand, epileptic activity is characterized by the paroxysmal depolarization shift, a hypersynchronous network event resulting from a giant excitatory postsynaptic potential. A paroxysmal depolarization shift is the correlate of. [sic] The EPSP is presumably the consequence of synchronous activation of recurrent excitatory pathways (Jonston and Brown, 1984). [...] SD is accompanied by a very large increase in [K+]o. The increase in [K+]o is accompanied by a precipitous drop in [Cl-]o, [Na+]o, and [Ca2+]o.
Anmerkungen

The source is not mentioned.

Note that also errors have been copied from the source: "In the other hand", The truncated sentence: "A paroxysmal depolarization shift is the correlate of."

Sichter
(Hindemith) Schumann

[2.] Aeh/Fragment 017 17 - Diskussion
Zuletzt bearbeitet: 2014-04-29 17:59:09 Singulus
Aeh, Fragment, Gesichtet, Gorji 2001, SMWFragment, Schutzlevel sysop, Verschleierung

Typus
Verschleierung
Bearbeiter
Hindemith
Gesichtet
Yes.png
Untersuchte Arbeit:
Seite: 17, Zeilen: 17-23
Quelle: Gorji 2001
Seite(n): 38, Zeilen: l.col: 20ff
It was postulated that the excitatory amino acid glutamate plays a role in the chain of events triggering SD (Bures et al., 1974). The neocortex releases excitatory amino acids including glutamate and aspartate, to the extracellular space during CSD (Van Harreveld and Kooiman, 1965). Subsequently it has been shown that the triggering of SD requires activation of the NMDA subtype of glutamate receptor in rat cerebral cortex (Bures et al., 1974), in chick retina (Seeling, 1993) and in human neocortical tissues (Gorji et al., 2001). Other glutamate subreceptor (AMPA, kainate and quisqualate) can induce SD but their initiation inhibited by [NMDA receptor antagonist (Lauritzen et al., 1988).]

Bures J., Buresova O., Krivanek J. In: The Mechanisms and Applications of Leao’s Spreading Depression of Electroencephalographic Activity, Academic Press, New York (1974).

Gorji A, Scheller D, Straub H, Tegtmeier F, Köhling R, Höhling JM, Tuxhorn I, Ebner A, Wolf P, Werner Panneck H, Oppel F, Speckmann EJ. Spreading depression in human neocortical slices. Brain Res. 2001;906:74-83.

Lauritzen M, Rice ME, Okada Y, Nicholson C. Quisqualate, kainate and NMDA can initiate spreading depression in the turtle cerebellum. Brain Res. 1988; 475:317–327.

Seelig MS, Interrelationship of magnesium and estrogen in cardiovascular and bone disorders, eclampsia, migraine and premenstrual syndrome. J. Am. Coll. Nutr. 1993;12:442–458.

Van Harreveld A, Kooiman M. Amino acid release from the cerebral cortex during spreading depression and asphyxiation. J. Neurochem. 1965;12:431–439.

It was postulated that the excitatory amino acid glutamate plays a role in the chain of events triggering SD [442,443]. The brain cortex releases excitatory amino acids including glutamate and aspartate, to the extracellular space during CSD [447]. Subsequently it has been shown that the triggering of SD requires activation of the NMDA subtype of glutamate receptor in rat cerebral cortex [147,261], in chick retina [380] and in human neocortical tissues [149]. Other glutamate receptor subtypes (AMPA, kainate and quisqualate) can induce SD but their effects inhibited by NMDA receptor antagonist [241,383].

[147] N.A. Gorelova, V.I. Koroleva, T. Amemori, V. Pavlik, J. Bures, Ketamine blockade of cortical spreading depression in rats, Electroencephalogr. Clin. Neurophysiol. 66 (1987) 440-447.

[149] A. Gorji, D. Scheller, H. Straub, F. Tegtmeier, A. Ebnen, P. Wolf, H.W. Panneck, F. Oppel, E.-J. Speckmann, R. Kohling, J. Hohling, I. Tuxhorn, Spreading depression in neocortical human slices, Brain Res. 906 (2001) 74-83.

[241] M. Lauritzen, M.E. Rice, Y. Okada, C. Nicholson, Quisqualate, kainate and NMDA can initiate spreading depression in the turtle cerebellum, Brain Res. 475 (1988) 317-327.

[261] R. Marrannes, R. Willems, E. De Prins, A. Wauquier, Evidence for a role of the N-metPyl-D-aspartate (NMDA) receptor in cortical spreading depression in the rat, Brain Res. 457 (1988) 226-240.

[380] M.S. Seelig, Interrelationship of magnesium and estrogen in cardiovascular and bone disorders, eclampsia, migraine and premenstrual syndrome, J. Am. Coll. Nutr. 12 (1993) 442-458.

[383] M.J. Sheardown, The triggering of spreading depression in the chicken retina: a pharmacological study, Brain Res. 607 (1993) 189-194.

[442] A. Van Harreveld, Compounds in brain extracts causing spreading depression of cerebral cortical activity and contraction of crustacean muscle, J. Neurochem. 3 (1959) 300-315.

[443] A. Van Harreveld, E. Fifkova, Glutamate release from the retina during spreading depression, J. Neurobiol. 2 (1970) 13-29.

[447] A. Van Harreveld, M. Kooiman, Amino acid release from the cerebral cortex during spreading depression and asphyxiation, J. Neurochem. 12 (1965) 431-439.

Anmerkungen

The source is not mentioned.

The correct Gorji et al. paper appears to have the title: "Spreading depression in human neocortical slices"; the other seems not to exist.

Sichter
(Hindemith) Singulus


vorherige Seite | zur Übersichtsseite | folgende Seite
Letzte Bearbeitung dieser Seite: durch Benutzer:Schumann, Zeitstempel: 20140429223943

Auch bei Fandom

Zufälliges Wiki