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Typus
Verschleierung
Bearbeiter
Schumann
Gesichtet
Yes.png
Untersuchte Arbeit:
Seite: 6, Zeilen: 5-15
Quelle: Somjen 2001
Seite(n): 1070, Zeilen: l.col: 15ff
The unparalleled increase in extracellular potassium concentration ([K+]o) is accompanied by a precipitous drop in extracellular chloride concentration ([Cl-]o), extracellular sodium concentration ([Na+]o), and extracellular calcium concentration ([Ca2+]o), suggesting that K+ leaving neurons is exchanged against Na+ and Ca2+ that are entering and increased up to 60 mM. [Ca2+]o decreases from its normal level of 1.2-1.5 mM to <0.3 mM. Cations are not exchanged one for one between intra- and extracellular solutions, for the reduction in [Na+]o is greater than the increase in [K+]o. The concomitant drop in [Cl-]o indicates that some of the Na+ entering the cells is accompanied by Cl. It has been suggested that the deficit in extracellular anions is made up by anions leaving the cytosol. Organic anions, including glutamate, have been shown to be released during SD, although some of the glutamate originates from glial cells. The unparalleled increase in [K+]o (35, 221, 232, 434) is accompanied by a precipitous drop in [Cl-]o, [Na+]o, and [Ca2+]o (78, 124, 128, 187, 281, 283, 373, 448), suggesting that K+ leaving cells is exchanged against Na+ and Ca2+ that are entering (281, 360). [Ca2+]o decreases from its normal level of 1.2-1.5 mM to ,0.3 mM. Cations are not exchanged one for one between intra- and extracellular solutions, for the reduction in [Na+]o is greater than the increase in [K+]o (267). The concomitant drop in [Cl-]o indicates that some of the Na+ entering the cells is accompanied by Cl-. Nicholson (281) suggested that the deficit in extracellular anions is made up by anions leaving the cytosol. Indeed, organic anions, including glutamate, have been shown to be released during SD (71, 81, 395, 397, 420), although some of the glutamate comes from glial cells (170, 171, 394).

[...]

Anmerkungen

No source is given.

Sichter
(Schumann), Hindemith

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