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Untersuchte Arbeit:
Seite: 17, Zeilen: 1-6
Quelle: Granz 2009
Seite(n): 19, 20, Zeilen: 19: 1-7 - 20: 1-3
Figure 4 Effects of quinpirole on cortical spreading depression (SD) in somatosensory neocortical tissues. A: Recording of DC potential shifts in the third layer of a neocortical slice before (A1), during (A2), and after (A3) application of quinpirole (50 μM). Field potentials were recorded by an ink-writer. SD was elicited by KCl microinjection. B: The curve indicates the plot of percentage enlargement of SD amplitude vs. quinpirole concentrations (n= 6 for each concentration). Quinpirole dose-dependently increased the amplitude of SD. The [percentage of SD amplitude enlargement was measured by division of the amplitude of SD induced after application of sulpiride to the amplitude of SD elicited before superfusion of the substance. Values represent mean ± SEM. Significance was determined by ANOVA test followed by Dunn’s post-test (B; P ≤ 0.001).] Fig. 4 Effects of somatostatin on cortical spreading depression (SD) in somatosensory neocortical tissues. A: Recording of DC potential shifts in the third layer of a neocortical slice before (A1), during (A2), and after (A3) application of somatostatin (500 nM). Field potentials were recorded by an ink-writer. SD was elicited by KCl microinjection. B: The curve indicates the plot of percentage decreases of SD amplitude vs. somatostatin concentrations (n = 8 for each concentration). Somatostatin dose-dependently decreased the amplitude of SD. The percentage of SD amplitude reduction was measured by division of 20 the amplitude of SD induced after application of somatostatin to the amplitude of SD elicited before superfusion of the substance. Values represent mean ± SEM. Significance was determined by ANOVA test followed by Dunn’s post-test (B; P ≤ 0.001).
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