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Typus
KomplettPlagiat
Bearbeiter
Graf Isolan
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Untersuchte Arbeit:
Seite: 2, Zeilen: 20-27
Quelle: Lou 2008
Seite(n): 3, Zeilen: 6-14
Although 99.9% of the human genomes are identical between people, there are still millions of differences among the 3.2 billion base pairs (Kruglyak and Nickerson, 2001). These genetic variations can cause phenotypic variations among people and are potentially associated with traits or diseases. Genetic markers, which are nucleotide variants with known positions, are often used for human disease analyses. Several types of markers exist, such as Restriction Fragment Length Polymorphisms (RFLP’s), microsatellites, and single nucleotide polymorphisms (SNPs). Markers can be used to construct a genetic map, which can be used as a reference for disease-[gene mapping (Dib et al., 1996).]

Dib, C., Fauré, S., Fizames, C., Samson, D., Drouot, N., Vignal, A., Millasseau, P., Marc, S., Hazan, J., Seboun, E. & others (1996) A comprehensive genetic map of the human genome based on 5,264 microsatellites. Nature, 380(6570): 152–154.

Kruglyak, L. & Nickerson, D. A. (2001) Variation is the spice of life. Nat Genet, 27(3): 234–236.

Across the human genome, about 99.9% of the genome is identical between people, but there are still millions of differences among the 3.2 billion base pairs (Kruglyak & Nickerson 2001). These genetic variations can cause phenotypic variation among people and are potentially associated with traits or diseases. Genetic markers, which are nucleotide variants with known positions, are often used for human disease analyses. There exist several types of genetic markers, for example, Restriction Fragment Length Polymorphisms (RFLP’s), microsatellites, and single nucleotide polymorphisms (SNPs). Markers can be used to construct a genetic map, which can be used as a reference for disease-gene mapping (Dib et al. 1996).

Dib, C., S. Faure, C. Fizames, D. Samson, N. Drouot et al. 1996 A comprehensive genetic map of the human genome based on 5,264 microsatellites. Nature 380: 152-154.

Kruglyak, L., and D. A. Nickerson, 2001 Variation is the spice of life. Nature Genetics 27: 234-236.

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