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Untersuchte Arbeit:
Seite: 3, Zeilen: 22-26
Quelle: Malik et al 2010
Seite(n): 1801, Zeilen: r. col. 7-13
Radiation therapy has played a minor role in the treatment of patients with liver cancer or liver metastases because the liver has been considered sensitive to radiation. Indeed, radiation-induced liver diseases (RILD) is a serious clinical complication (Shim et al. 2007), due chiefly to radiation-induced inflammation. Radiation induced liver damage seems to be worst if diseased liver is irradiated (Cheng et al. 2002).

Shim SJ, Seong J, Lee IJ, Han KH, Chon CY, Ahn SH (2007) Radiation-induced hepatic toxicity after radiotherapy combined with chemotherapy for hepatocellular carcinoma. Hepatol Res 37:906-913

Cheng JC, Wu JK, Huang CM, Huang DY, Cheng SH, Lin YM, Jian JJ, Yang PS, Chuang VP, Huang AT (2002) Radiation-induced liver disease after radiotherapy for hepatocellular carcinoma: clinical manifestation and dosimetric description. Radiother Oncol 63:41-45

Radiation therapy has played a minor role in the treatment of patients with liver cancer or liver metastases because the liver has been considered sensitive to radiation. Indeed, radiation-induced liver diseases is a serious clinical complication 1, due chiefly to radiation-induced inflammation. Radiation induced liver damage seems to be worst if diseased liver is irradiated 2.

1. Shim SJ, Seong J, Lee IJ, Han KH, Chon CY, Ahn SH: Radiation-induced hepatic toxicity after radiotherapy combined with chemotherapy for hepatocellular carcinoma. Hepatol Res 2007, 37:906-913

2. Cheng JC, Wu JK, Huang CM, Huang DY, Cheng SH, Lin YM, Jian JJ, Yang PS, Chuang VP, Huang AT: Radiation-induced liver disease after radiotherapy for hepatocellular carcinoma: clinical manifestation and dosimetric description. Radiother Oncol 2002, 63:41-45

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