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Typus
KomplettPlagiat
Bearbeiter
Graf Isolan
Gesichtet
Yes.png
Untersuchte Arbeit:
Seite: 4, Zeilen: 3-10
Quelle: Moriconi et al 2008
Seite(n): 162, Zeilen: left col. 29-35 - right col. 1-2.12-15
The interest of gastroenterologists, radiation oncologists and pathologists in radiation-induced liver disease has been generated by clinical observations of the deterioration of liver function occurring after abdominal irradiation with at least 30 Gy in patients with chronic liver diseases or even in patients with a healthy liver. This toxicity limits the use of radioimmunotherapy for malignant lymphomas, radio-chemotherapy for biliopancreatic carcinomas, and radiotherapy for liver malignancies (Greco et al. 2004;Wang et al. 1995). The molecular pathogenesis of hepatocellular damage after irradiation and the development of radiation-induced liver disease is still unknown.

Greco C, Catalano G, Di GA, Orecchia R (2004) Radiotherapy of liver malignancies. From whole liver irradiation to stereotactic hypofractionated radiotherapy. Tumori 90:73-79

Wang S, Quadri SM, Tang XZ, Stephens LC, Lollo CP, Bartholomew RM, Vriesendorp HM (1995) Liver toxicity induced by combined external-beam irradiation and radioimmunoglobulin therapy. Radiat Res 141:294-302

Introduction

The interest of gastroenterologists, radiation oncologists and pathologists in radiation-induced liver disease has been generated by clinical observations of the deterioration of liver function occurring after abdominal irradiation with at least 30 Gy in patients with chronic liver diseases or even in patients with a healthy liver. This toxicity limits the use of radioimmunotherapy for malignant lymphomas, radio-chemotherapy for biliopancreatic carcinomas, and radiotherapy for liver malignancies (1-3).

[...] The molecular pathogenesis of hepatocellular damage after irradiation and the development of radiation-induced liver disease is still unknown.


1. S. Wang, S. M. Quadri, X. Z. Tang, L. C. Stephens, C. T. Lollo, R. M. Bartholomew and H. M. Vriesendorp, Liver toxicity induced by combined external-beam irradiation and radioimmunoglobulin therapy. Radiat. Res. 141, 294–302 (1995).

2. C. Sempoux, Y. Horsmans, A. Geubel, J. Fraikin, B. E. Van Beers, J. F. Gigot, J. Lerut and J. Rahier, Severe radiation-induced liver disease following localized radiation therapy for biliopancreatic carcinoma: activation of hepatic stellate cells as an early event. Hepatology 26, 128–134 (1997).

3. C. Greco, G. Catalano, A. Di Grazia and R. Orecchia, Radiotherapy of liver malignancies. From whole liver irradiation to stereotactic hypofractionated radiotherapy. Tumori 90, 73–79 (2004).

Anmerkungen

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Sichter
(Graf Isolan) Schumann

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