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Typus
KomplettPlagiat
Bearbeiter
Hindemith
Gesichtet
Yes.png
Untersuchte Arbeit:
Seite: 11, Zeilen: 12-17
Quelle: Christiansen et al 2007
Seite(n): 190, Zeilen: col 2: 29-41
Investigators have shown that hepatocytes are not substantially damaged by radiation. Still, radiation can weaken the defense mechanisms of hepatocytes, and this weakening can lead to the susceptibility to apoptosis mediated by tumor necrosis factor alpha (TNF-α) in-vitro in some hepatocytes (Christiansen et al. 2004). Furthermore, results of a recent study indicate that whole-liver irradiation in the rat leads to development of steatosis within the first 48 hours after irradiation (Christiansen et al. 2006).

Christiansen H, Batusic D, Saile B, Hermann RM, Dudas J, Rave-Frank M, Hess CF, Schmidberger H, Ramadori G (2006) Identification of genes responsive to gamma radiation in rat hepatocytes and rat liver by cDNA array gene expression analysis. Radiat Res 165:318-325

Christiansen H, Saile B, Neubauer-Saile K, Tippelt S, Rave-Frank M, Hermann RM, Dudas J, Hess CF, Schmidberger H, Ramadori G (2004) Irradiation leads to susceptibility of hepatocytes to TNF-alpha mediated apoptosis. Radiother Oncol 72:291-296

Investigators have shown that hepatocytes are not substantially damaged by radiation. Still, radiation can weaken the defense mechanisms of hepatocytes, and this weakening can lead to the susceptibility to apoptosis mediated by tumor necrosis factor α (TNF-α) in vitro in some hepatocytes (30). Furthermore, results of a recent study indicate that whole-liver irradiation in the rat leads to development of steatosis within the first 48 hours after irradiation (31).

30. Christiansen H, Saile B, Neubauer-Saile K, et al. Irradiation leads to susceptibility of hepatocytes to TNF-alpha mediated apoptosis. Radiother Oncol 2004;72:291–296.

31. Christiansen H, Batusic D, Saile B, et al. Identification of genes responsive to gamma radiation in rat hepatocytes and rat liver by cDNA array gene expression analysis. Radiat Res 2006;165:318–325.

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Sichter
(Hindemith) Schumann

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