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Typus
Verschleierung
Bearbeiter
Graf Isolan
Gesichtet
Yes.png
Untersuchte Arbeit:
Seite: 11, Zeilen: 22-28
Quelle: Sheikh 2006
Seite(n): 7, Zeilen: 12-16; 22-24
Once it became obvious that the liver is injured after irradiation, the individual liver cell types would be introduced in culture to investigate a hierarchy of the events triggering after irradiation in the liver. Besides the ability to respond to the cytokine action, liver parenchyma and non-parenchaymal cells express a great variety of receptors for chemokines, cytokines, growth factors, and prostaglandins and represent therefore the major target for a multiple set of mediators involved in defense reaction after liver irradiation (Christiansen et al. 2007).

Christiansen H, Sheikh N, Saile B, Reuter F, Rave-Frank M, Hermann RM, Dudas J, Hille A, Hess CF, Ramadori G (2007) x-Irradiation in rat liver: consequent upregulation of hepcidin and downregulation of hemojuvelin and ferroportin-1 gene expression. Radiology 242:189-197

Once it became obvious that the liver is a primary target organ for the APR, the individual liver cell types were introduced in culture to investigate a hierarchy of the events triggering the full APR in the liver. Besides the ability to respond to the cytokine action, different cell types within the liver are also able to express IL-1β, TNF-α, IL-6, and other modulator cytokines of the hepatic APR (Ramadori and Christ, 1999). [...] Hepatocytes express a great variety of receptors for cytokines, growth factors, and prostaglandins and therefore, represent the major target for a multiple set of mediators involved in both systemic and local host defense reactions.

Ramadori G and Christ B. Cytokines and the hepatic acute-phase response. Semin Liver Dis 19: 141-155, 1999.

Anmerkungen

Adapted to fit Iam's subject, but still in large parts identical. Nothing has been marked as a citation.

Sichter
(Graf Isolan) Schumann

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