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[1.] Ib/Fragment 018 01 - Diskussion
Zuletzt bearbeitet: 2016-07-14 20:50:26 WiseWoman
Fragment, Gesichtet, Ib, KomplettPlagiat, Mohamed 2009, SMWFragment, Schutzlevel sysop

Typus
KomplettPlagiat
Bearbeiter
SleepyHollow02
Gesichtet
Yes.png
Untersuchte Arbeit:
Seite: 18, Zeilen: 1-8
Quelle: Mohamed 2009
Seite(n): 19, 20, Zeilen: 19: 18 ff.; 20: 1 ff.
[And (5) based on information gained through population structure, correlation of phenotypic and genotypic/haplotypic data with the application of an appropriate statistical approach that reveals, consequently a specific gene(s) controlling a] QTL of interest can be cloned using the marker tags and annotated for an exact biological function. Association mapping offers three main advantages: increased mapping resolution, reduced research time, and greater allele numbers (Reich et al. 2001).

Association mapping, also known as linkage disequilibrium mapping, is a relatively new and promising genetic method for complex trait dissection. Association mapping has the promise of higher mapping resolution through exploitation of historical recombination events at the population level that may enable gene level mapping on non-model organisms where linkage based approaches would not be feasible (Varshney and Tuberosa 2007).


Reich DE, Cargill M, Bolk S et al. (2001) Linkage disequilibrium in the human genome. Nature, vol. 411, No. 6834: 199–204

Varshney RK and Tuberosa R (2007) Application of linkage disequilibrium and association mapping in crop plants. Genomics Approaches and Platforms, Vol 1: 97 – 119

And (5) based on information gained through population structure, correlation of phenotypic and genotypic/haplotypic data with the application of an appropriate statistical approach that reveals, consequently a specific gene(s) controlling a QTL of interest can be cloned using the marker tags and annotated for an exact biological function.

[...]

Compared to linkage mapping in traditional bioparental populations, association mapping offers three main advantages: increased mapping resolution, reduced research time, and greater allele numbers (Reich et al. 2001).

[page 20]

Association mapping, also known as linkage disequilibrium mapping, is a relatively new and promising genetic method for complex trait dissection. Association mapping has the promise of higher mapping resolution through exploitation of historical recombination events at the population level that may enable gene level mapping on non-model organisms where linkage based approaches would not be feasible (Varshney and Tuberosa. 2007).


Reich DE, Cargill M, Bolk S, Ireland J, Sabeti PC, Richter DJ, Lavery T, Kouyoumjian R, Farhadian S, Ward R, Lander ES (2001) Linkage disequilibrium in the human genome. Nature, vol. 411, No. 6834: 199–204

Varshney RK, Tuberosa R (2007) Application of linkage disequilibrium and association mapping in crop plants. Genomics Approaches and Platforms, Vol 1: 97 – 119.

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