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| Untersuchte Arbeit: Seite: 281, Zeilen: 1-5 |
Quelle: Nadel et al 2007 Seite(n): 2, Zeilen: l.col: 22-28 |
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| [Evidence supporting this view comes from] neuroimaging studies showing that retrieval of detailed episodic memories activates the hippocampus irrespective of how old these memories are (e.g., Maguire et al., 2001; Rekkas & Constable, 2005) and from studies showing that remote episodic memories retrieved by amnesic patients lack the detail present in remote episodic memories of an individual with an intact hippocampus (Moscovitch et al., 2005).
Maguire, E.A., Vargha-Khadem, F., & Mishkin, M. (2001). The effects of bilateral hippocampal damage on fMRI regional activations and interactions during memory retrieval. Brain, 124, 1156–1170. Moscovitch, M., Rosenbaum, R.S., Gilboa, A., Addis, D.R., Westmacott, R., & Grady, C. (2005). Functional neuroanatomy of remote episodic and semantic and spatial memory: a unified account based on multiple trace theory. Journal of Anatomy, 207, 35–66. Rekkas, P.V. & Constable, T. (2005). Evidence that autobiographical memory retrieval does not become independent of the hippocampus: An fMRI study contrasting very recent with remote events. Journal of Cognitive Neuroscience, 17, 1950–1961. |
Evidence supporting this view comes from neuroimaging studies showing that retrieval of detailed episodic memories activates the hippocampus no matter how old these memories are [14–18] and from studies showing that remote episodic memories retrieved by amnesic patients lack the detail present in remote episodic memories retrieved by an individual with an intact hippocampus [19].
[14] E. A. Maguire, R. N. A. Henson, C. J. Mummery, and C. D. Frith, “Activity in prefrontal cortex, not hippocampus, varies parametrically with the increasing remoteness of memories,” NeuroReport, vol. 12, no. 3, pp. 441–444, 2001. [15] R. Lee, L. Nadel, and K. Keil, “Hippocampal complex and retrieval of recent and very remote autobiographical memories: evidence from functional magnetic resonance imaging in neurologically intact people,” Hippocampus, vol. 11, no. 6, pp. 707–714, 2001. [16] A. Gilboa, G. Winocur, C. L. Grady, S. J. Hevenor, and M. Moscovitch, “Remembering our past: functional neuroanatomy of recollection of recent and very remote personal events,” Cerebral Cortex, vol. 14, no. 11, pp. 1214–1225, 2004. [17] S. Steinvorth, B. Levine, and S. Corkin, “Medial temporal lobe structures are needed to re-experience remote autobiographical memories: evidence from H.M. and W.R.,” Neuropsychologia, vol. 43, no. 4, pp. 479–496, 2005. [18] P. V. Rekkas and R. T. Constable, “Evidence that autobiographical memory retrieval does not become independent of the hippocampus: an fMRI study contrasting very recent with remote events,” Journal of Cognitive Neuroscience, vol. 17, no. 12, pp. 1950–1961, 2005. [19] M. Moscovitch, R. S. Rosenbaum, A. Gilboa, et al., “Functional neuroanatomy of remote episodic, semantic and spatial memory: a unified account based on multiple trace theory,” Journal of Anatomy, vol. 207, no. 1, pp. 35–66, 2005. |
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