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Crosstalk between autoreactive T cells and alveolar type II epithelial cells in inflammation and tolerance

von Dr. Marcus Gereke

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[1.] Mag/Fragment 003 01 - Diskussion
Zuletzt bearbeitet: 2014-03-10 12:15:55 Graf Isolan
BauernOpfer, Bienenstock and McDermott 2005, Fragment, Gesichtet, Mag, SMWFragment, Schutzlevel sysop

Typus
BauernOpfer
Bearbeiter
Hindemith
Gesichtet
Yes.png
Untersuchte Arbeit:
Seite: 3, Zeilen: 1-11
Quelle: Bienenstock and McDermott 2005
Seite(n): 22, Zeilen: 1ff
The bronchus-associated lymphoid tissue (BALT) constitutes organized lymphoid aggregates of T and B cell that are capable to respond against to inhaled antigens. BALT, located mostly at bifurcations of the bronchus in animals and humans, is already present in the fetus and develops rapidly following birth, especially in the presence of antigens. Humoral immune responses elicited by BALT are based primarily in immunoglobulin A secretion, locally and by BALT-derived B cells that have trafficked to distant mucosal sites. Similarly, located T cell responses have been noted. On the basis of these findings, the BALT can be thought of as functionally analogous to mucosal lymphoid aggregates in the intestine and is deemed a member of the common mucosal immunologic system (Bienenstock and McDermott, 2005). The bronchus-associated lymphoid tissue (BALT) and the nasal-associated lymphoid tissue (NALT) constitute organized lymphoid aggregates that are capable of T- and B-cell responses to inhaled antigens. BALT, located mostly at bifurcations of the bronchus in animals and humans, is present in the fetus and develops rapidly following birth, especially in the presence of antigens. Humoral immune responses elicited by BALT are primarily immunoglobulin A secretion both locally and by BALT-derived B cells that have trafficked to distant mucosal sites. Similarly located T-cell responses have been noted. On the basis of these findings, the BALT can be thought of as functionally analogous to mucosal lymphoid aggregates in the intestine and is deemed a member of the common mucosal immunologic system.
Anmerkungen

The source is given at the end, but it is not clear to the reader that the entire paragraph is taken from the source and that is has been taken more or less literally.

Sichter
(Hindemith), PlagProf:-)


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Letzte Bearbeitung dieser Seite: durch Benutzer:Graf Isolan, Zeitstempel: 20140310121653

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