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Typus
BauernOpfer
Bearbeiter
PlagProf:-)
Gesichtet
Yes.png
Untersuchte Arbeit:
Seite: 13, Zeilen: 17-20
Quelle: Fehrenbach_2001
Seite(n): 40, Zeilen: r.col: 35ff
The best example for a cell-cell interaction between AECII and resident cells is the direct contact with AECI and during proliferation with AECII neighbours as well. These lateral cell-cell contacts within the alveolar epithelium are maintained by cell junction complex that includes gap junctions (Kasper et al, 1996). Additionally, AECII [have direct contact to fibroblasts at the basal membrane or with capillary endothelial cells (Marin et al., 1982).]

Kasper M, Traub O, Reimann T, Bjermer L, Grossmann H, Muller M, Wenzel KW Upregulation of gap junction protein connexin43 in alveolar epithelial cells of rats with radiation-induced pulmonary fibrosis. Histochem Cell Biol. 1996 Oct; 106 (4): 419-24.

Marin L, Dameron F, Relier JP. Changes in the cellular environment of differentiating type II pneumocytes. Quantitative study in the perinatal rat lung. Biol Neonate. 1982; 41 (3-4): 172-82.

Interaction with resident cells

First of all, the AE2 cell is in direct contact with AE1 cells and during proliferation with AE2 cell neighbours as well. These lateral cell-cell contacts within the alveolar epithelium are maintained by a cell junction complex that includes gap junctions [142]. The basal cell membrane is in close proximity to fibroblasts, in particular during the canalicular phase of lung morphogenesis, while modelling of the alveolar septum results in an increase in the spatial relationship of the AE2 cells with capillary endothelial cells of the adult lung [143].


142. Kasper M, Traub O, Reimann T, Bjermer L, Grossmann H, Müller M, Wenzel KW: Upregulation of gap junction protein connexin43 in alveolar epithelial cells of rats with radiationinduced pulmonary fibrosis. Histochem Cell Biol 1996, 106: 419–424.

143. Marin L, Dameron F, Relier JP: Changes in the cellular environment of differentiating type II pneumocytes. Quantitative study in the perinatal rat lung. Biol Neonate 1982, 41:172–182.

Anmerkungen

Following one reference to Fehrenbach for having termed type II epithelial cells "as integrative units of the alveolus", the author adopts over pp. 13-16 an uninterrupted review of some 30 articles from Fehrenbach without indicating this source.

Sichter
Hindemith

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