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New insights into the pathogenic mechanisms associated with CNVs: duplication of 17p13.3, mirror effect in 16p11.2 and recessive phenotype in 22q11.22

von Dott. Mafalda Mucciolo

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[1.] Mmu/Fragment 007 01 - Diskussion
Zuletzt bearbeitet: 2014-12-11 20:41:12 SleepyHollow02
Fragment, Gesichtet, KomplettPlagiat, Mmu, Papa 2010, SMWFragment, Schutzlevel sysop

Typus
KomplettPlagiat
Bearbeiter
Graf Isolan
Gesichtet
Yes
Untersuchte Arbeit:
Seite: 7, Zeilen: 1-7
Quelle: Papa 2010
Seite(n): 12, Zeilen: Fig 2:1-9
Fig.2 Schematic representation of an array-CGH experiment. Test and reference DNA are differentially labelled, co-precipitated and hybridised to an array. After wash procedures, the slides are analysed through a scanner and fluorescence intensities of each probe are determined. After imaging processing and data normalization, the log2 ratios of the probes are plotted as a function of chromosomal position. Probes with a value of zero represent equal fluorescence intensity ratio between sample and reference. In this representation, copy number loss shift the ratio to the left and copy number gains shift the ratio to the right. Fig. 2 Schematic representation of an array-CGH experiment. a) Test and reference DNA are differentially labelled, co-precipitated and hybridised to an array. b) and c) After wash procedures, the slides are analysed through a scanner and fluorescence intensities of each probe are determined. d) After imaging processing and data normalization, the log2 ratios of the probes are plotted as a function of chromosomal position. Probes with a value of zero represent equal fluorescence intensity ratio between sample and reference. [...] In this representation, copy number loss shift the ratio to the left and copy number gains shift the ratio to the right.
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Sichter
(Graf Isolan), SleepyHollow02



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Letzte Bearbeitung dieser Seite: durch Benutzer:Singulus, Zeitstempel: 20141207215509