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| Untersuchte Arbeit: Seite: 10, Zeilen: 12 (Tabelle) |
Quelle: Reschner et al 2008 Seite(n): 220, Zeilen: 0 |
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| Table 1: Populations of DCs in mice and humans.
DC subsets Tissue distribution Species Immature phenotype Mature phenotype Bone marrow derived DC Dermis, airways, intestine, thymus, spleen, liver, lymphoid tissue Mouse CD11c+CD8α- CD11b+MHCII+ TLR-1–3+/−TLR-2,4–9+ CD83+ CCR7+ CD80++ CD86++ MHCII++ Human CD1a+ CD14- CD11c++CD11b++ CD1c+ CD209+ MHC-II+ TLR-1, 6+,3,8++ CD40+ Plasmacytoid DC Lymphoid organs, liver, lung, skin Mouse CD11c+/−B220+Ly-6C+CD11b- PDCA+ MHC-II+ TLR-2–9+ Human CD14-CD11c-CD123++ BDCA2+ ILT7+ MHC-II+ TLR-7,9++ CD8α+DC Thymus, spleen, lymph node, liver Mouse CD8α+CD4-CD11c++ CD11b CD205++-TLR-2–4,6,8,9+ Human Not identified Langerhans cells Mucosal epithelia, epidermis Mouse CD8α- CD11c+ CD205++ Ecadherin+ CD207+ E-cadherin +/− Human CD14+/−CD11c+CD1a+ Ecadherin+ CD207+CCR6+ DC, dendritic cells. +/−, low; ++, high. |
Table 1. Populations of DC in mice and humans. DC subsets Tissue distribution Species Immature phenotype Mature phenotype Bone marrow derived DC Dermis, airways, intestine, thymus, spleen, liver, lymphoid tissue Mouse CD11c+CD8a- CD11b+MHC-II+ TLR-1–3+/-TLR-2,4–9+ CD83+ CCR7+ CD80++ CD86++ MHC-II++ Human CD1a+ CD14-CD11c++CD11b++ CD1c+ CD209+ MHC-II+ TLR-1, 6+,3,8++ CD40+ Plasmacytoid DC Lymphoid organs, liver, lung, skin Mouse CD11c+/-B220+Ly-6C+CD11b- PDCA+ MHC-II+ TLR-2–9+ Human CD14-CD11c-CD123+ + BDCA2+ ILT7+ MHC-II+ TLR-7,9++ CD8a+DC Thymus, spleen, lymph node, liver Mouse CD8a+CD4-CD11c++ CD11b CD205++ -TLR-2–4,6,8,9+ Human Not identified Langerhans cells Mucosal epithelia, epidermis Mouse CD8a- CD11c+ CD205++ E-cadherin+CD207+ E-cadherin +/- Human CD14+/-CD11c+CD1a+ E-cadherin+CD207+CCR6+ DC, dendritic cells. +/-, low; ++, high. |
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