Fandom

VroniPlag Wiki

Pak/Fragment 016 06

< Pak

31.354Seiten in
diesem Wiki
Seite hinzufügen
Diskussion5 Share

Störung durch Adblocker erkannt!


Wikia ist eine gebührenfreie Seite, die sich durch Werbung finanziert. Benutzer, die Adblocker einsetzen, haben eine modifizierte Ansicht der Seite.

Wikia ist nicht verfügbar, wenn du weitere Modifikationen in dem Adblocker-Programm gemacht hast. Wenn du sie entfernst, dann wird die Seite ohne Probleme geladen.


Typus
Verschleierung
Bearbeiter
Hindemith
Gesichtet
Yes.png
Untersuchte Arbeit:
Seite: 16, Zeilen: 6-18
Quelle: Wikipedia hematopoietic stem cell 2008
Seite(n): 1 (online source), Zeilen: -
Using limiting dilution strategies combined with other streamlined experimental and statistical methods for examining HSCs at the clonal level, HSCs fall into three distinct lineage-biased clusters.56-58 These are quantitatively defined by the ratio “ρ” of lymphoid to myeloid cells that the HSC generates upon differentiation (which makes ñ [sic] a peripheral predictor for the clonal association of a reconstituted haematopoietic system). Balanced HSCs repopulate peripheral white blood cells in the same ratio of myeloid to lymphoid cells as seen in unmanipulated mice (on average about 15% myeloid and 85% lymphoid cells, or 3≤ñ≤10 [sic]), in the NOD/SCID mice. Myeloid-biased (My-bi) HSC give rise to too few lymphocytes resulting in ratios 0<ρ<3, whereas lymphoid-biased (Ly-bi) HSC generate too few myeloid cells, which results in lymphoid-to-myeloid ratios of 10<ρ<00 [sic]. All three types are normal HSCs in the sense that they have self-renewal capacity and can regenerate all haematopoietic lineages (pluripotency).

56. Muller-Sieburg [sic] CE, Cho RH, Thoman M, Adkins B, Sieburg HB. Deterministic regulation of hematopoietic stem cell self-renewal and differentiation. Blood. 2002;100:1302-1309.

57. Muller-Sieburg [sic] CE, Cho RH, Karlsson L, Huang JF, Sieburg HB. Myeloid-biased hematopoietic stem cells have extensive self-renewal capacity but generate diminished lymphoid progeny with impaired IL-7 responsiveness. Blood. 2004;103:4111-4118.

58. Sieburg HB, Cho RH, Dykstra B, Uchida N, Eaves CJ, Muller-Sieburg [sic] CE. The hematopoietic stem compartment consists of a limited number of discrete stem cell subsets. Blood. 2006;107:2311-2316.

Using limiting dilution strategies combined with other streamlined experimental and statistical methods for examining HSCs at the clonal level, it was shown that HSCs fall into three distinct lineage-bias[1] [2] [3] clusters. These are quantitatively defined by the ratio ρ of lymphoid to myeloid cells that HSC generate upon differentiation (which makes ρ a peripheral predictor for the clonal association of a reconstituted hematopoietic system). Balanced HSCs repopulate peripheral white blood cells in the same ratio of myeloid to lymphoid cells as seen in unmanipulated mice (on average about 15% myeloid and 85% lymphoid cells, or 3≤ρ≤10). Myeloid-biased (My-bi) HSC give rise to too few lymphocytes resulting in ratios 0<ρ<3, whereas lymphoid-biased (Ly-bi) HSC generate too few myeloid cells, which results in lymphoid-to-myeloid ratios of 10 < ρ < oo. All three types are normal HSC in that they have self-renewal capacity and can regenerate all hematopietic [sic] lineages (pluripotency).

1. Muller-Sieburg [sic] CE, Cho RH, Thoman M, Adkins B, Sieburg HB, Deterministc [sic] regulation of hematopoietic stem cell self-renewal and differentiation. Blood. 2002; 100; 1302-9

2. Muller-Sieburg [sic] CE, Cho RH, Karlson [sic] L, Huang JF, Sieburg HB. Myeloid-biased hematopoietic stem cells have extensive self-renewal capacity but generate diminished progeny with impaired IL-7 responsiveness. Blood. 2004; 103:4111-8.

3. Sieburg HB, Cho RH, Dykstra B, [sic] Eaves, CJ, Muller-Sieburg [sic], CE. The hematopoietic stem cell [sic] compartment consists of a limited number of discrete stem cell subsets. Blood. 2006; 107:2311-6. Epub 2005 Nov 15.

Anmerkungen

The source is not given.

Note that in the thesis the copied passage has a smaller line spacing than the normal text in the thesis. However there is no indication that the passage might have been taken from anywhere else.

Sichter
(Hindemith) Singulus

Auch bei Fandom

Zufälliges Wiki