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Autor     Belinda R. Avalos
Titel    Molecular Analysis of the Granulocyte Colony-Stimulating Factor Receptor
Zeitschrift    Blood
Herausgeber    The American Society of Hematology
Ausgabe    88
Datum    1. August 1996
Nummer    3
Seiten    761-777
ISSN    0006-4971
URL    http://bloodjournal.hematologylibrary.org/content/88/3/761.full.pdf

Literaturverz.   

yes
Fußnoten    yes
Fragmente    2


Fragmente der Quelle:
[1.] Arc/Fragment 016 09 - Diskussion
Zuletzt bearbeitet: 2014-02-26 23:10:40 Guckar
Arc, Avalos 1996, Fragment, Gesichtet, SMWFragment, Schutzlevel sysop, Verschleierung

Typus
Verschleierung
Bearbeiter
Hindemith
Gesichtet
Yes
Untersuchte Arbeit:
Seite: 16, Zeilen: 9-16
Quelle: Avalos 1996
Seite(n): 761, Zeilen: l.col: 20ff
The immature neutrophils that arise from bone marrow follow a process that involves proliferation, differentiation along the granulocyte lineage and terminal maturation into functional neutrophils. Many other hematopoietic growth factors like stem cell factor (SCF), IL-3, GM-CSF, IL-6, have been shown to be positive regulators of granulopoiesis and act at different stages of myeloid cell development. But, G-CSF is unique among the regulators of granulopoiesis, because it not only stimulates the proliferation but also potently induces the terminal maturation of myeloid progenitor cells to neutrophilic granulocytes1.

1. Basu S, Dunn A, Ward A. G-CSF: function and modes of action (Review). Int J Mol Med. 2002;10:3-10.

Mature neutrophils arise from bone marrow (BM) stem cells following a process involving proliferation, commitment to differentiation along the granulocyte lineage, and terminal maturation.5 Several hematopoietic growth factors including stem cell factor (SCF), interleukin-3 (IL-3), granulocyte-macrophage colony-stimulating factor (GM-CSF), IL-6, and G-CSF have been shown to be positive regulators of granulopoiesis and act at different stages of myeloid cell development.6,7 [...] G-CSF is unique among the regulators of granulopoiesis in that it not only stimulates the proliferation but also potently induces the terminal maturation of myeloid progenitor cells to neutrophilic granulocytes.

[...]

Anmerkungen

The source is given before this passage, but without any indication that the text after the reference is taken from it.

Sichter
(Hindemith) Singulus


[2.] Arc/Fragment 017 16 - Diskussion
Zuletzt bearbeitet: 2014-02-26 23:10:55 Guckar
Arc, Avalos 1996, Fragment, Gesichtet, KomplettPlagiat, SMWFragment, Schutzlevel sysop

Typus
KomplettPlagiat
Bearbeiter
Hindemith
Gesichtet
Yes
Untersuchte Arbeit:
Seite: 17, Zeilen: 16-27
Quelle: Avalos 1996
Seite(n): 763, Zeilen: figure
17a diss

Fig. 2 – A: Schematic diagram of the structure of the human G-CSFR. The extracellular region (EX) of the G-CSFR contains an Ig-like domain, a cytokine receptor homologous region (CRH) with conserved cysteine (C) residues and the WSXWS motif, and three fibronectin type III (Fn3) domains. The intracellular domain (ID) of the G-CSFR contains three subdomains, designated boxes 1,2, and 3. Numbers correspond to amino acid residues. TM, transmembrane domain; Y, tyrosine residues24.


24. Nagata S, Fukunaga R. Granulocyte colony-stimulating factor and its receptor. Prog Growth Factor Res. 1991;3:131-141.

17a source

Fig 1. Schematic diagram of the structure of the hG-CSFR. The extracellular region (EX) of the G-CSFR contains an Ig-like domain, a cytokine receptor homologous region (CRH) with conserved cysteine (C) residues and the WSXWS motif, and three fibronectin type III (Fn3) domains. The intracellular domain (ID) of the G-CSFR contains three subdomains designated boxes 1,2, and 3 [...]. Numbers correspond to amino acid residues. TM, transmembrane domain; Y, tyrosine residues.

Anmerkungen

The source is not given. The copied material cannot be found in Nagata & Fukunaga (1991)

Sichter
(Hindemith) Singulus