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Angaben zur Quelle [Bearbeiten]

Autor     Manjit S. Matharu, Christopher J. Boes and Peter J. Goadsby
Titel    Management of Trigeminal Autonomic Cephalgias and Hemicrania Continua
Zeitschrift    Drugs
Ausgabe    63
Jahr    2003
Nummer    16
URL    http://content.lib.utah.edu/utils/getfile/collection/ehsl-nam/id/745/filename/746.pdf

Literaturverz.   

no
Fußnoten    no
Fragmente    1


Fragmente der Quelle:
[1.] Clg/Fragment 024 08 - Diskussion
Zuletzt bearbeitet: 2014-05-11 16:02:47 Schumann
Clg, Fragment, Gesichtet, Matharu et al 2003, SMWFragment, Schutzlevel sysop, Verschleierung

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Untersuchte Arbeit:
Seite: 24, Zeilen: 8-15
Quelle: Matharu et al 2003
Seite(n): 12, Zeilen: l. col. 26-41
Intravenous somatostatin (25 μg/min for 20 min) was compared with treatment with ergotamine (250 μg intramuscularly), or placebo in a double-blind trial comprising 72 attacks in eight patients (Sicuteri et al., 1984). Infusion of somatostatin reduced the maximal pain intensity and the duration of pain to a level comparable with intramuscular ergotamine. In a randomized, double-blind study subcutaneous somatostatin was compared with ergotamine (Geppetti et al., 1985). Five patients were treated for three attacks by each of the drugs. Subcutaneous somatostatin and ergotamine were equally beneficial as regards effects on maximal pain intensity and the pain area, but somatostatin was less effective in reduction of the duration of headache.

Sicuteri F, Geppetti P, Marabini S, Lembeck F (1984) Pain relief by somatostatin in attacks of cluster headache. Pain 18(4):359-65.

Intravenous somatostatin 25 μg/min for 20 minutes was compared with ergotamine 250μg intramuscularly or placebo in a double-blind trial comprising 72 attacks in eight patients. [102] Infusion of somatostatin reduced the maximal pain intensity and the duration of pain significantly compared with placebo, and to a degree comparable to intramuscular ergotamine.

In another randomised, double-blind study, subcutaneous somatostatin was compared with ergotamine. [102] Five patients were treated for three attacks by each of the drugs. Subcutaneous somatostatin and ergotamine were equally beneficial as regards effects on maximal pain intensity and the pain area, but somatostatin was less effective in reducing the duration of pain.


[102] Sicuteri F. Geppetti P, Marabini S, et al. Pain relief by somatostatin in attacks of cluster headache. Pain 1984; 18: 359-65

[103] Geppetti P, Brocchi A, Caleri D, et al. Somatostatin for cluster beadache attack. In: Pfaffenrath V, Lundberg PO, Sjaastad O, editors. Updating in headache. Berlin: Spring-Verlag, 1985: 302-5

Anmerkungen

The source named "Geppetti et al., 1985" is missing in the chapter "VI. References".

Different spelling: "randomized" instead of "randomised" – a hint that the text also could have been taken from another source.

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