Angaben zur Quelle [Bearbeiten]
| Autor | Hans Christiansen, Danko Batusic, Bernhard Saile, Robert Michael Hermann, Jozsef Dudas, Margret Rave-Fränk, Clemens Friedrich Hess, Heinz Schmidberger, Giuliano Ramadorib |
| Titel | Identification of Genes Responsive to Gamma Radiation in Rat Hepatocytes and Rat Liver by cDNA Array Gene Expression Analysis |
| Zeitschrift | Radiation research |
| Herausgeber | Radiation Research Society |
| Ausgabe | 165 |
| Jahr | 2006 |
| Seiten | 318-325 |
| URL | http://www.ncbi.nlm.nih.gov/pubmed/16494520 |
Literaturverz. |
yes |
| Fußnoten | yes |
| Fragmente | 3 |
| [1.] Iam/Fragment 011 08 - Diskussion Zuletzt bearbeitet: 2014-03-19 21:33:48 Hindemith | Christiansen et al 2006, Fragment, Iam, KeineWertung, SMWFragment, Schutzlevel, ZuSichten |
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| Untersuchte Arbeit: Seite: 11, Zeilen: 8-12 |
Quelle: Christiansen et al 2006 Seite(n): 318, Zeilen: right col. 4-5, 14-17, 19-21 |
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| The threshold dose for injury after whole-liver irradiation has been reported to be between 20 and 30 Gy (Anscher et al. 1990). In animal studies, liver irradiation above a threshold dose is not followed by a recovery phase and a complete return to normal. Instead, progressive liver fibrosis and cirrhosis may occur (Geraci et al. 1993).
Anscher MS, Crocker IR, Jirtle RL (1990) Transforming growth factor-beta 1 expression in irradiated liver. Radiat Res 122:77-85 Geraci JP, Mariano MS, Jackson KL (1993) Radiation hepatology of the rat: time-dependent recovery. Radiat Res 136:214-221 |
The threshold dose for injury after whole-liver irradiation is thought to be between 20 and 30 Gy (9). [...]
[...] In animal studies, an initial inflammatory reaction after irradiation above the threshold dose is not followed by a recovery phase and complete restitution. Instead, progressive liver fibrosis and cirrhosis are regularly found (13). 9. R. L. Jirtle, M. S. Anscher and T. Alati, Radiation sensitivity of the liver. Adv. Radiat. Biol. 14, 269–311 (1990). 13. J. P. Geraci, M. S. Mariano and K. L. Jackson, Radiation hepatology of the rat: Time-dependent recovery. Radiat. Res. 136, 214–221 (1993). |
Not marked as a citation, no source given. |
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| [2.] Iam/Fragment 011 17 - Diskussion Zuletzt bearbeitet: 2014-03-12 19:42:49 Graf Isolan | Christiansen et al 2006, Fragment, Gesichtet, Iam, KomplettPlagiat, SMWFragment, Schutzlevel sysop |
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| Untersuchte Arbeit: Seite: 11, Zeilen: 17-21 |
Quelle: Christiansen et al 2006 Seite(n): 318, Zeilen: right col. 9-13 |
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| The acute clinical period of radiation-induced liver disease after irradiation tends to be relatively silent; the subacute phase is characterized by the development of anicteric ascites, elevation of liver enzymes, rapid weight gain, and liver enlargement 2 weeks to 4 months after treatment (Lawrence et al. 1995).
Lawrence TS, Robertson JM, Anscher MS, Jirtle RL, Ensminger WD, Fajardo LF (1995) Hepatic toxicity resulting from cancer treatment. Int J Radiat Oncol Biol Phys 31:1237-1248 |
The acute clinical period of radiation-induced liver disease after irradiation tends to be relatively silent; the subacute phase is characterized by the development of anicteric ascites, elevation of liver enzymes, rapid weight gain, and liver enlargement 2 weeks to 4 months after treatment (12).
12. T. S. Lawrence, J. M. Robertson, M. S. Anscher, R. L. Jirtle, W. D. Ensminger and L. F. Fajardo, Hepatic toxicity resulting from cancer treatment. Int. J. Radiat. Oncol. Biol. Phys. 31, 1237–1248 (1995). |
Identical, not marked as a citation, no source given. |
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| [3.] Iam/Fragment 074 20 - Diskussion Zuletzt bearbeitet: 2014-03-12 19:42:43 Graf Isolan | Christiansen et al 2006, Fragment, Gesichtet, Iam, SMWFragment, Schutzlevel sysop, Verschleierung |
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| Untersuchte Arbeit: Seite: 74, Zeilen: 20-21 |
Quelle: Christiansen et al 2006 Seite(n): 318, Zeilen: right col. 28-30 |
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| Gene array analysis of RNA from irradiated tissues is an effective tool for identifying genes of potential interest in the development of tissue injury (Kruse et al. 2004).
Kruse JJ, te Poele JA, Russell NS, Boersma LJ, Stewart FA (2004) Microarray analysis to identify molecular mechanisms of radiation-induced microvascular damage in normal tissues. Int J Radiat Oncol Biol Phys 58:420-426 |
Gene array analysis of RNA from irradiated tissues is an effective tool for identifying genes of potential interest in the development of normal tissue injury (15).
15. J. J. Kruse, J. A. Te Poele, N. S. Russell, L. J. Boersma and F. A. Stewart, Microarray analysis to identify molecular mechanisms of radiation-induced microvascular damage in normal tissues. Int. J. Radiat. Oncol. Biol. Phys. 58, 420–426 (2004). |
From the final chapter of Iam's thesis ("Discussion"): Nearly identical with identical reference; not marked as a citation; no source given. |
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