Fandom

VroniPlag Wiki

Quelle:Mmu/Kalman and Vitale 2009

< Quelle:Mmu

31.371Seiten in
diesem Wiki
Seite hinzufügen
Diskussion0

Störung durch Adblocker erkannt!


Wikia ist eine gebührenfreie Seite, die sich durch Werbung finanziert. Benutzer, die Adblocker einsetzen, haben eine modifizierte Ansicht der Seite.

Wikia ist nicht verfügbar, wenn du weitere Modifikationen in dem Adblocker-Programm gemacht hast. Wenn du sie entfernst, dann wird die Seite ohne Probleme geladen.

Angaben zur Quelle [Bearbeiten]

Autor     Bernadette Kalman, Emilia Vitale
Titel    Structural Chromosomal Variations in Neurological Diseases
Zeitschrift    The Neurologist
Ausgabe    15
Jahr    2009
Nummer    5
ISSN    1074-7931/09/1505-0245
DOI    10.1097/NRL.0b013e3181963cef
URL    http://journals.lww.com/theneurologist/Abstract/2009/09000/Structural_Chromosomal_Variations_in_Neurological.3.aspx

Literaturverz.   

no
Fußnoten    no
Fragmente    2


Fragmente der Quelle:
[1.] Mmu/Fragment 088 12 - Diskussion
Zuletzt bearbeitet: 2014-11-19 19:33:01 Singulus
Fragment, Gesichtet, Kalman and Vitale 2009, KomplettPlagiat, Mmu, SMWFragment, Schutzlevel sysop

Typus
KomplettPlagiat
Bearbeiter
Hindemith
Gesichtet
Yes.png
Untersuchte Arbeit:
Seite: 88, Zeilen: 12-22
Quelle: Kalman and Vitale 2009
Seite(n): 247, Zeilen: l. col: 10 ff.
The presence of a CNVs in a coding region usually correlates with changes in the abundance of corresponding transcripts. Absence or excess of the protein product of a dosage sensitive gene may influence cell differentiation or migration and tissue formation early during development. In addition, genomic rearrangements may also be associated with molecular mechanisms other than affecting transcript levels to influence gene dosage and expression. Such complex mechanisms include gene interruption, gene fusion, unmasking a recessive allele or silenced gene, and interruption of regulatory gene-gene and chromosomal interactions (Lupski and Stankiewicz 2005). Even before the completion of the Human Genome Project, the pathogenic significance of gene dosage was realized in several disorders of the central and peripheral nervous system.

44. Lupski JR & Stankiewicz P. 2005.Genomic disorders: Molecular mechanisms for rearrangements and conveyed phenotypes. PLoS Genet 1:e49.

The presence of a CNV in a coding region usually correlates with changes in the abundance of corresponding transcripts. Absence or excess of the protein product of a dosage sensitive gene may influence cell differentiation or migration and tissue formation early during development. [...]

In addition, genomic rearrangements may also be associated with molecular mechanisms other than affecting transcript levels to influence gene dosage and expression. Such complex mechanisms include gene interruption, gene fusion, unmasking a recessive allele or silenced gene, and interruption of regulatory gene-gene and chromosomal interactions.5 [...]

[...]

[...] Even before the completion of the Human Genome Project, the pathogenic significance of gene dosage was realized in several disorders of the central and peripheral nervous system (CNS, PNS).


5. Lee JA, Lupski JR. Genomic rearrangements and gene copy-number alterations as a cause of nervous system disorders. Neuron. 2006;52:103–121.

Anmerkungen

The source is not mentioned. Lupski and Stankiewicz (2005) does not contain the parallel text.

Sichter
(Hindemith), SleepyHollow02

[2.] Mmu/Fragment 089 16 - Diskussion
Zuletzt bearbeitet: 2014-11-19 19:29:01 Singulus
Fragment, Gesichtet, Kalman and Vitale 2009, Mmu, SMWFragment, Schutzlevel sysop, Verschleierung

Typus
Verschleierung
Bearbeiter
Hindemith
Gesichtet
Yes.png
Untersuchte Arbeit:
Seite: 89, Zeilen: 16-18
Quelle: Kalman and Vitale 2009
Seite(n): 251, Zeilen: r.col: 25 ff.
The highlighted examples demonstrate how gene dosage effects may influence the development of common disorders often characterized by heterogeneous genetic aetiology. The highlighted examples demonstrate how gene dosage effects may influence cell function and development of common disorders often characterized by heterogeneous genetic etiology.
Anmerkungen

The source is not mentioned.

Sichter
(Hindemith), SleepyHollow02

Auch bei Fandom

Zufälliges Wiki