Fandom

VroniPlag Wiki

Quelle:Ww/Zou and Yoder 2005

< Quelle:Ww

31.373Seiten in
diesem Wiki
Seite hinzufügen
Diskussion0

Störung durch Adblocker erkannt!


Wikia ist eine gebührenfreie Seite, die sich durch Werbung finanziert. Benutzer, die Adblocker einsetzen, haben eine modifizierte Ansicht der Seite.

Wikia ist nicht verfügbar, wenn du weitere Modifikationen in dem Adblocker-Programm gemacht hast. Wenn du sie entfernst, dann wird die Seite ohne Probleme geladen.

Angaben zur Quelle [Bearbeiten]

Autor     Gang-Ming Zou, Mervin C. Yoder
Titel    Application of RNA interference to study stem cell function: current status and future perspectives
Zeitschrift    Biology of the cell
Verlag    Wiley
Ausgabe    97
Jahr    2005
Seiten    211-219
DOI    10.1042/BC20040084
URL    http://onlinelibrary.wiley.com/doi/10.1042/BC20040084/abstract

Literaturverz.   

nein
Fußnoten    nein
Fragmente    1


Fragmente der Quelle:
[1.] Ww/Fragment 007 07 - Diskussion
Zuletzt bearbeitet: 2014-10-29 17:07:06 Hindemith
Fragment, Gesichtet, SMWFragment, Schutzlevel sysop, Verschleierung, Ww, Zou and Yoder 2005

Typus
Verschleierung
Bearbeiter
Hindemith
Gesichtet
Yes.png
Untersuchte Arbeit:
Seite: 7, Zeilen: 7-21
Quelle: Zou and Yoder 2005
Seite(n): 211, Zeilen: l.col: 2ff
RNA interference (RNAi) was a term coined by Fire and coworkers to describe the inhibition of gene expression by double-stranded RNAs (dsRNAs) when introduced into nematode worms (Caenorhabditis elegans). Following on from the studies of Guo and Kemphues (1995), who had found that sense RNA was as effective as antisense RNA for suppressing gene expression in worms, Fire et al. (1998) applied single-stranded antisense RNA and double stranded RNA in their experiments. To their surprise, they found that dsRNA was more effective in producing interference than was either strand individually. After injection into adult C. elegans, single-stranded antisense RNA had a modest effect in diminishing specific gene expression, whereas double-stranded mixtures caused potent and specific interference.

Today we know that RNAi is a multistep process involving the generation of small interfering RNAs (siRNAs) in vivo through the action of the RNase III endonuclease “Dicer”. The resulting 21- to 23-nt siRNAs mediate the degradation of their complementary RNA (Shi, 2003).

RNA interference (RNAi) was a term coined by Fire and coworkers (1998) to describe the inhibition of gene expression by double-stranded RNAs (dsRNAs) when introduced into nematode worms (Caenorhabditis elegans). Following on from the studies of Guo and Kemphues (1995), who had found that sense RNA was as effective as antisense RNA for suppressing gene expression in worms, Fire et al. (1998) applied single-stranded antisense RNA and double stranded RNA in their experiments. To their surprise, they found that dsRNA was more effective at producing interference than was either strand individually. After injection into adult C. elegans, single-stranded antisense RNA had a modest effect in diminishing specific gene expression, whereas double-stranded mixtures caused potent and specific interference (Fire et al., 1998). RNAi is a multistep process involving the generation of small interfering RNAs (siRNAs) in vivo through the action of the RNase III endonuclease ‘Dicer’. The resulting 21- to 23-nt siRNAs mediate degradation of their complementary RNA (Shi, 2003).
Anmerkungen

Ein Verweis auf die Quelle fehlt.

Sichter
(Hindemith) Klgn

Auch bei Fandom

Zufälliges Wiki