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| Untersuchte Arbeit: Seite: 10, Zeilen: 13-16 |
Quelle: Balk and Knudsen 2008 Seite(n): 2, Zeilen: left col. 18-22 |
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| While the subsets of AR target genes that underlie each cellular outcome have yet to be clearly defined, discovery of at least one major AR-dependent target gene, prostate specific antigen (PSA) has had a major impact on disease management (12).
10) Riegman PH, Vlietstra RJ, van der Korput JA, Brinkmann AO, Trapman J The promoter of the prostate-specific antigen gene contains a functional androgen responsive element. Mol Endocrinol.1991 Dec;5(12):1921-30. 12) Ryan CJ, Smith A, Lal P, Satagopan J, Reuter V, Scardino P, Gerald W, Scher HI. Persistent prostate-specific antigen expression after neoadjuvant androgen depletion: an early predictor of relapse or incomplete androgen suppression Urology. 2006 Oct;68(4):834-9 |
While the subsets of AR target genes that underlie each cellular outcome have yet to be clearly defined, discovery of at least one major AR-dependent target gene, prostate specific antigen (PSA) [Riegman et al., 1991], has had a major impact on disease management.
Riegman, P. H., Vlietstra, R. J., van der Korput, J. A., Brinkmann, A. O. and Trapman, J. (1991) The promoter of the prostate-specific antigen gene contains a functional androgen responsive element Mol Endocrinol 5, 1921-30. |
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