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Permeation of Organometallic Compounds through Phospholipid Membranes

von Dr. Raycho Yonchev

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[1.] Ry/Fragment 006 01 - Diskussion
Zuletzt bearbeitet: 2016-01-23 14:18:02 WiseWoman
Anézo 2003, Fragment, Gesichtet, KomplettPlagiat, Ry, SMWFragment, Schutzlevel sysop

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KomplettPlagiat
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Klgn
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Quelle: Anézo 2003
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Ry 006 diss.png

Figure 1.2. Generic structure of phospholipids. The phosphate can be esterified to the various X-groups listed to form the different classes of phospholipids.

1,2-Diacylglyceroophospholipids [sic] or phospholipids. These fatty acid esters of glycerol are the predominant lipids in most biomembranes. The phosphate is usually linked to one of the several groups listed in Figure 1.2, including choline, ethanolamine, the S-amino acid serine, and polyalcohols such as glycerol or inositol. The corresponding phospholipids are called phosphatidylcholines (commonly abbreviated PC), phosphatidylethanolamines (PE), phosphatidylserines (PS), phosphatidylglycerols (PG) and phosphatidylinositols (PI). PC and PE constitute the major components of biomembranes. The chemical structure of these polar headgroups determines what charge the phospholipid as a whole may carry. At physiological pH values, PC and PE carry a full negative charge on the phosphate and a full positive charge on the quaternary [ammonium – they are thus zwitterionic but electrically neutral. PS contain in addition to the negatively charged phosphate and the positively charged amino group, a negatively charged carboxyl group.]

Ry 006 source.png

Figure 1.3: Generic structure of phospholipids. The phosphate can be esterified to the various X-groups listed to form the different classes of phospholipids.

  • 1,2-Diacylglycerophospholipids or phospholipids These fatty acid esters of glycerol are the predominant lipids in most biomembranes. The phosphate is usually linked to one of the several groups listed in Figure 1.3, including choline, ethanolamine, the S-amino acid serine, and polyalcohols such as glycerol or inositol. The corresponding phospholipids are called phosphatidylcholines (commonly abbreviated PC), phosphatidylethanolamines (PE), phosphatidylserines (PS), phosphatidylglycerols (PG), and phosphatidylinositols (PI). PC and PE constitute the major components of biological membranes. The chemical structure of these polar headgroups determines what charge the phospholipid as a whole may carry. At physiological pH values, PC and PE carry a full negative charge on the phosphate and a full positive charge on the quaternary ammonium: they are thus zwitterionic but electrically neutral. PS contain, in addition to the negatively charged phosphate and the positively charged amino group, a negatively charged carboxyl group.
Anmerkungen

No source is given.

Sichter
(Klgn), WiseWoman


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