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Membrane androgen receptor activation triggers pro-apoptotic responses in vitro and in vivo and blocks migration in colon cancer

von S. G.

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[1.] Shg/Fragment 021 18 - Diskussion
Zuletzt bearbeitet: 2014-11-02 08:57:03 Hindemith
Fragment, Gesichtet, Li Lai 2009, SMWFragment, Schutzlevel sysop, Shg, Verschleierung

Typus
Verschleierung
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SleepyHollow02
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Untersuchte Arbeit:
Seite: 21, Zeilen: 18-27
Quelle: Li Lai 2009
Seite(n): 219, Zeilen: right col., 3 ff.
According to the Surveillance, Epidemiology and End Results (SEER) Program database analysis, 5-year survival rates have risen from 56.5% for patients diagnosed in the early 1980s to as much as 63.2% for those diagnosed in the early 1990s and most recently to 64.9%, a trend due mostly to earlier diagnosis and treatment [Ries LAG, et al. 2008]. One reason for the improving trend is that the prognosis for patients with CRC is highly dependent on stage: 5-year survival rates are over 90% for Dukes A, but only 5% for Dukes D. Unfortunately, only 10% of CRCs are diagnosed early, most patients presenting themselves with the advanced disease [Rockville, MD. 1998].

Ries LAG, Melbert D, Krapcho M, et al. (2008). SEER Cancer Statistics Review. National Cancer Institute: 1975-2005.

Rockville, MD. (1998). Agency for Health Care Policy and Research. AHCPR Publication No. 98-003.

According to the Surveillance, Epidemiology and End Results (SEER) Program database analysis, 5-year survival rates have risen from 56.5% for patients diagnosed in the early 1980s to as much as 63.2% for those diagnosed in the early 1990s and most recently to 64.9%, a trend due mostly to earlier diagnosis and treatment (Ries et al., 2008). One reason for the improving trend is that the prognosis for patients with CRC is highly dependent on stage: 5-year survival rates are over 90% for Dukes A, but only 5% for Dukes D. Unfortunately, only 10% of CRCs are diagnosed early, most patients presenting themselves with advanced disease (AHCPR, 1998)

Ries, L.A.G., Melbert, D., Krapcho, M., Stinchcomb, D.G., Howlader, N., Horner, M.J., Mariotto, A., Miller, B.A., Feuer, E.J., Altekruse, S.F., Lewis, D.R., et al. (Eds.), 2008. SEER Cancer Statistics Review, 1975-2005 [WWW]. National Cancer Institute. Available from: http://seer.cancer.gov/csr/1975_2005/results_merged/topic_survival.pdf [Accessed 06/08/2008].

AHCPR (Agency for Health Care Policy and Research), 1998. Colorectal Cancer Screening. Technical Review 1. AHCPR Publication No. 98-0033. Agency for Health Care Policy and Research, Rockville, MD.

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(SleepyHollow02), Hindemith


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