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| Untersuchte Arbeit: Seite: 6, Zeilen: 4-11 |
Quelle: Uldry and Thorens 2004 Seite(n): 480, Zeilen: l.col: 30ff |
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| Facilitated diffusion of glucose and related hexoses across biological membranes is catalysed by members of the SLC2 family, referred to as glucose transporters or GLUTs. These transporters function as simple carriers and the movement of hexose across the plasma membrane proceeds in the direction imposed by its electrochemical gradient. A common structural feature of the SLC2 family members is the presence of 12 transmembrane domains (TM) with both the amino and carboxy-terminal ends present on the cytosolic side and a unique N-linked oligosaccharide side-chain present either in the first or the fourth extracellular loop (16).
16. Mueckler,M, Makepeace,C: Transmembrane segment 12 of the Glut1 glucose transporter is an outer helix and is not directly involved in the transport mechanism. J.Biol.Chem. 281:36993-36998, 2006 |
Facilitated diffusion of glucose and related hexoses across biological membranes is catalysed by members of the SLC2 family, referred to as glucose transporters or GLUTs. These transporters function as simple carriers and the movement of hexose across the plasma membrane proceeds in the direction imposed by its electrochemical gradient. A common structural feature of the SLC2 family member is the presence of 12 transmembrane domains (TM) with both the amino and carboxy-terminal ends present on the cytosolic side and a unique N-linked oligosaccharide side-chain present either in the first or the fourth extracellular loop. |
The source given does not contain the parallel text. |
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