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Typus
KomplettPlagiat
Bearbeiter
Graf Isolan
Gesichtet
Yes.png
Untersuchte Arbeit:
Seite: 35, Zeilen: 1-8
Quelle: Sajikumar 2005
Seite(n): 36, Zeilen: 10-14, 17-21
[Late-LTP was induced] on one pathway (S1), and the protein synthesis inhibitor anisomycin was then bath applied just before the second pathway (S2) was tetanised. Normally, only early-LTP would be induced and late-LTP inhibited in the presence of anisomycin. However, the LTP induced on S2 remained potentiated for up to 8 h post-tetanus. Similarly, “weak” tetanic stimulation that normally induces only early-LTP could be ‘transformed’ into late-LTP heterosynaptically if a “strong” tetanus was delivered to an independent input to the same population of CA1 pyramidal cells shortly before or shortly after the weak tetanus (Frey and Morris, 1998b).

59. Frey U, Morris RG (1998b) Weak before strong: dissociating synaptic tagging and plasticity-factor accounts of late-LTP. Neuropharmacology 37: 545-552.

Late-LTP was induced on one pathway (S1), and the protein synthesis inhibitor anisomycin then bath applied just before the second pathway (S2) was tetanised. Normally, only early-LTP would be induced and late-LTP inhibited in the presence of anisomycin. However, the LTP induced on S2 remained potentiated for up to 8 h post-tetanus (Frey and Morris, 1997).

[...] The weak tetanic stimulation that normally induces only early-LTP could be ‘transformed’ into late-LTP heterosynaptically if a strong tetanus was delivered to an independent input to the same population of CA1 pyramidal cells shortly before or shortly after the weak tetanus (Frey and Morris, 1998b).


Frey U, Morris RG (1997) Synaptic tagging and long-term potentiation. Nature 385: 533-536.

Frey U, Morris RG (1998b) Weak before strong: dissociating synaptic tagging and plasticity-factor accounts of late-LTP. Neuropharmacology 37: 545-552.

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