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Typus
Verschleierung
Bearbeiter
Hindemith
Gesichtet
Yes.png
Untersuchte Arbeit:
Seite: 13, Zeilen: 1-11
Quelle: Wernsmann et al 2006
Seite(n): 1103, Zeilen: r.col: 7-22
[As memories in humans depend initially on the medial temporal lobe system, including the] hippocampus, it was suggested that interictal memory dysfunction in patients with migraine might be attributed to the hippocampus involvement (Kupfermann, 1966). Furthermore, propagation of SD in the hippocampus was believed to play a role in migraine pain by triggering nociceptive activation of the caudal trigeminal nucleus (Kunkler and Kraig, 2003). Classical studies investigated hippocampal SD more often by implantation of KCl into the hippocampus and induction of SD directly in the tissue. Little information is available on the effects of cortical SD on hippocampal activity. Because altered neural circuit function can be seen remote from the SD propagation site, using in vitro brain models, the effects of different substances as well as electrical stimulation on propagation of SD between the neocortex and the hippocampus was investigated. As memories in humans depend initially on the medial temporal lobe system, including the hippocampus, it was suggested that interictal memory dysfunction in patients with migraine might be attributed to the hippocampus involvement (Kupfermann, 1966; Kapp & Schneider, 1971). Furthermore, propagation of SD in the hippocampus was believed to play a role in migraine pain by triggering nociceptive activation of the caudal trigeminal nucleus (Kunkler & Kraig, 2003). Classical studies investigated hippocampal SD more often by implantation of KCl into the hippocampus and induction of SD directly in the tissue. Little information is available on the effects of cortical spreading depression (CSD) on hippocampal activity. Because altered neural circuit function can be seen remote from the SD propagation site (Bures et al., 1961; Albe-Fessard et al., 1984; Moskowitz et al., 1993; Kunkler & Kraig, 2003; Gorji et al., 2004), using in vitro and ex vivo / in vitro brain models, the effects of neocortical SD on the synaptic plasticity of hippocampal tissues were tested.
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Sichter
(Hindemith) Agrippina1

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