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Ectopic expression of the homeobox gene Cdx2 is the key transforming event in a mouse model of t(12;13)(p13;q12) acute myeloid leukemia; a novel mechanism in AML

von Dr. Vpr

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[1.] Vpr/Fragment 002 07 - Diskussion
Zuletzt bearbeitet: 2014-03-17 12:28:58 Graf Isolan
Fragment, Gesichtet, KomplettPlagiat, Lessard et al 2004, SMWFragment, Schutzlevel sysop, Vpr

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KomplettPlagiat
Bearbeiter
Hindemith
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Untersuchte Arbeit:
Seite: 2, Zeilen: 7-11
Quelle: Lessard_et_al_2004
Seite(n): 7199, Zeilen: l.col: 23-29
The first evidence for the existence of such a cell-type came from experiments by Ray Owen and co-workers in 1945, which showed that bovine fraternal twins, sharing a single placenta and blood circulation, retained production of blood cells genetically defined to be from both throughout their life. The first evidence for the existence of such a cell-type came from experiments by Ray Owen and co-workers, in 1945, which showed that bovine fraternal twins, sharing a single placenta and blood circulation, retained production of blood cells genetically defined to be from both throughout their life (Owen, 1945).
Anmerkungen

The source is not mentioned anywhere in the thesis.

Sichter
(Hindemith) Schumann

[2.] Vpr/Fragment 002 19 - Diskussion
Zuletzt bearbeitet: 2014-03-17 12:29:04 Graf Isolan
Fragment, Gesichtet, Lessard et al 2004, SMWFragment, Schutzlevel sysop, Verschleierung, Vpr

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Seite: 2, Zeilen: 19-25
Quelle: Lessard_et_al_2004
Seite(n): 7199, Zeilen: r.col: 31-39
The first attempts at purifying HSCs came from experiments carried out by Till and McCullogh in the Netherlands (Van Bekkum et. al., 1979; Worton et. al., 1969). Based on their work, it has become possible to routinely identify and isolate highly purified murine and human HSCs based mainly on characteristic cell surface proteins that are either present (Sca1 and c-kit) or absent (using markers of lineage committed cells such as CD38, Mac-1 and CD8) (Weissman, 2002).

Van Bekkum, D. W., van den Engh, G. J., Wagemaker, G., Bol, S. J., and Visser, J. W. (1979).
Structural identity of the pluripotential hemopoietic stem cell. Blood Cells 5, 143-159.

Weissman, I. L. (2002).
The road ended up at stem cells. Immunol Rev 185, 159-174.

Worton, R. G., McCulloch, E. A., and Till, J. E. (1969).
Physical separation of hemopoietic stem cells differing in their capacity for self-renewal. J Exp Med 130, 91-103.

The first attempts at purifying the HSC came from experiments carried out by Till and McCullogh (Worton et al., 1969; van Bekkum et al., 1979) in the Netherlands. From this work, it has become possible to routinely identify and isolate highly purified murine and human HSCs based mainly on characteristic cell surface proteins that are either present (Sca-1 and c-kit) or absent (using markers of lineage committed cells such as CD38, Mac-1 and CD8) (reviewed in Weissman, 2002).

van Bekkum DW, van den Engh GJ, Wagemaker G, Bol SJ and Visser JW. (1979). Blood Cells, 5, 143–159.

Weissman IL. (2002). Immunol. Rev., 185, 159–174.

Worton RG, McCulloch EA and Till JE. (1969). J. Exp. Med., 130, 91–103.

Anmerkungen

The source is not mentioned anywhere in the thesis.

Sichter
(Hindemith) Schumann

[3.] Vpr/Fragment 002 26 - Diskussion
Zuletzt bearbeitet: 2014-03-17 12:28:44 Graf Isolan
Fragment, Gesichtet, Reya et al 2001, SMWFragment, Schutzlevel sysop, Verschleierung, Vpr

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Untersuchte Arbeit:
Seite: 2, Zeilen: 26-31
Quelle: Reya et al 2001
Seite(n): 105, Zeilen: r.col: 23-31
In the hematopoietic system, stem cells are heterogeneous with respect to their ability to self-renew and can be divided into three different populations: long-term self-renewing HSCs, short-term self-renewing HSCs, and multipotent progenitors without detectable self-renewal potential (Morrison and Weissman, 1994; Morrison et. al., 1997). These populations form a lineage in which the long-term HSCs give rise to short-term HSCs, which in turn give rise to multi-[potent progenitors (Morrison et. al., 1997).]

Morrison, S. J., Wandycz, A. M., Hemmati, H. D., Wright, D. E., and Weissman, I. L. (1997). Identification of a lineage of multipotent hematopoietic progenitors. Development 124, 1929-1939.

Morrison, S. J., and Weissman, I. L. (1994). The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype. Immunity 1, 661-673.

In the haematopoietic system, stem cells are heterogeneous with respect to their ability to self-renew. Multipotent progenitors constitute 0.05% of mouse bone-marrow cells, and can be divided into three different populations: long-term self-renewing HSCs, short-term self-renewing HSCs, and multipotent progenitors without detectable self-renewal potential2,11. These populations form a lineage in which the long-term HSCs give rise to short-term HSCs, which in turn give rise to multipotent progenitors11.

2. Morrison, S. J. & Weissman, I. L. The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype. Immunity 1, 661–673 (1994).

11. Morrison, S. J., Wandycz, A. M., Hemmati, H. D., Wright, D. E. & Weissman, I. L. Identification of a lineage of multipotent hematopoietic progenitors. Development 124, 1929–1939 (1997).

Anmerkungen

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(Hindemith) Schumann


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