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Typus
Verschleierung
Bearbeiter
Hindemith
Gesichtet
Yes.png
Untersuchte Arbeit:
Seite: 2, Zeilen: 19-25
Quelle: Lessard_et_al_2004
Seite(n): 7199, Zeilen: r.col: 31-39
The first attempts at purifying HSCs came from experiments carried out by Till and McCullogh in the Netherlands (Van Bekkum et. al., 1979; Worton et. al., 1969). Based on their work, it has become possible to routinely identify and isolate highly purified murine and human HSCs based mainly on characteristic cell surface proteins that are either present (Sca1 and c-kit) or absent (using markers of lineage committed cells such as CD38, Mac-1 and CD8) (Weissman, 2002).

Van Bekkum, D. W., van den Engh, G. J., Wagemaker, G., Bol, S. J., and Visser, J. W. (1979).
Structural identity of the pluripotential hemopoietic stem cell. Blood Cells 5, 143-159.

Weissman, I. L. (2002).
The road ended up at stem cells. Immunol Rev 185, 159-174.

Worton, R. G., McCulloch, E. A., and Till, J. E. (1969).
Physical separation of hemopoietic stem cells differing in their capacity for self-renewal. J Exp Med 130, 91-103.

The first attempts at purifying the HSC came from experiments carried out by Till and McCullogh (Worton et al., 1969; van Bekkum et al., 1979) in the Netherlands. From this work, it has become possible to routinely identify and isolate highly purified murine and human HSCs based mainly on characteristic cell surface proteins that are either present (Sca-1 and c-kit) or absent (using markers of lineage committed cells such as CD38, Mac-1 and CD8) (reviewed in Weissman, 2002).

van Bekkum DW, van den Engh GJ, Wagemaker G, Bol SJ and Visser JW. (1979). Blood Cells, 5, 143–159.

Weissman IL. (2002). Immunol. Rev., 185, 159–174.

Worton RG, McCulloch EA and Till JE. (1969). J. Exp. Med., 130, 91–103.

Anmerkungen

The source is not mentioned anywhere in the thesis.

Sichter
(Hindemith) Schumann

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